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2007 Publications
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Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual J-F, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Solé X, Hernández P, Lázaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber SB, Parvin JD, Vidal M.
Network modeling links breast cancer susceptibility and centrosome dysfunction.
Nat Genet 2007; 39: 1338-49.
Preview, Cancer Cell
Highlight, Nature Reviews Genetics
Highlight, Nature Reviews Cancer
DFCI News
Faculty of 1000 Biology
Faculty of 1000 Medicine
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Kerrien S, Orchard S, Montecchi-Palazzi L, Aranda B, Quinn AF, Vinod N, Bader GD, Xenarios I, Wojcik J, Sherman D, Tyers M, Salama JJ, Moore S, Ceol A, Chatr-aryamontri A, Oesterheld M, Stümpflen V, Salwinski L, Nerothin J, Cerami E, Cusick, M, Vidal M, Gilson M, Armstrong J, Woollard P, Hogue C, Eisenberg D, Cesareni G, Apweiler R, Hermjakob H.
Broadening the Horizon-Level 2.5 of the HUPO-PSI Format for Molecular Interactions.
BMC Biology 2007; 5:44. |
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Wang H, Segal E, Ben-Hur A, Li Q, Vidal M, Koller D.
InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale.
Genome Biol 2007; 8:R192. |
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Orchard S, Salwinski L, Kerrien S, Montecchi-Palazzi L, Oesterheld M, Stümpflen V, Ceol A, Chatr-aryamontri A, Armstrong J, Woollard P, Salama JJ, Moore S, Wojcik J, Bader G, Vidal, M, Cusick ME, Gerstein M, Gavin A-C, Superti-Furga G, Greenblatt J, Bader J, Uetz P, Tyers M, Legrain P, Fields S, Mulder N, Gilson M, Niepmann M, Burgoon L, De Las Rivas J, Prieto C, Perreau VM, Hogue C, Mewes H-W, Apweiler R, Xenarios I, Eisenberg D, Cesareni G, Hermjakob H.
The minimum infomation required for reporting a molecular interaction experiment (MIMIx).
Nat Biotechnol 2007; 25:894-8.
Editorial, Nature Biotechnology
Research Highlight, Nature Methods
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Simarro M, Mauger D, Rhee K, Pujana MA, Kedersha NL, Yamasaki S, Cusick ME, Vidal M, Garcia-Blanco MA, Anderson P.
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing.
Proc Natl Acad Sci USA 2007; 104:11370-11375.
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Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC.
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Cell 2007; 129:1065-1079.
Commentary, Cell |

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Bertin N, Simonis N, Dupuy D, Cusick ME, Han JD, Fraser HB, Roth FP, Vidal M.
Confirmation of organized modularity in the yeast interactome.
PLoS Biol 2007; 5:e153.
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Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabasi AL.
The human disease network.
Proc Natl Acad Sci USA 2007; 104:8685-8690.
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Dupuy D, Bertin N, Hidalgo CA, Venkatesan K, Tu D, Lee D, Rosenberg J, Svrzikapa N, Blanc A, Carnec A, Carvunis A,
Pulak R, Shingles J, Reece-Hoyes J, Hunt-Newbury R, Viveiros R, Mohler WA,
Tasan M, Roth FP, Le Peuch C, Hope IA, Johnsen R, Moerman DG, Barabasi AL, Baillie D & Vidal M.
Genome-scale analysis of in vivo spatiotemporal
promoter activity in Caenorhabditis elegans.
Nat Biotechnol 2007; 25:663-668.
News & Views, Nature Biotechnology |

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Calderwood MA, Vekatesan K, Xing L, Chase MR, Vazquez A, Holthaus AM, Ewence AE, Li N, Hirozane-Kishikawa T, Hill DE, Vidal M, Kieff E, Johannsen E.
Epstein-Barr virus and virus human protein interaction maps.
Proc Natl Acad Sci USA 2007;104:7606-11.
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Rual JF, Klitgord N, Achaz G.
Novel insights into RNAi off-target effects using C. elegans paralogs.
BMC Genomics 2007;8:106.
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Ceron J, Rual JF, Chandra A, Dupuy D, Vidal M, van den Heuval S.
Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity.
BMC Dev Biol 2007;7:30.
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Lamesch P, Li N, Milstein S, Fan C, Hao T, Szabo G, Hu Z, Venkatesan K, Bethel G, Martin P, Rogers J, Lawlor S, McLaren S, Dricot A, Cusick ME, Vandenhaute J, Dunham I, Hill DE, Vidal M. hORFeome 3.1: a resource of human open reading frames covering over 10,000 human genes.
Genomics 2007;89:307-15.
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St Onge RP, Mani R, Oh J, Proctor M, Fung E, Davis R, Nislow C, Roth FP, Giaver G.
Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions.
Nat Genet 2007;39:199-206.
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Reece-Hoyes JS, Shingles J, Dupuy D, Grove CA, Walhout AJ, Vidal M, Hope IA.
Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns.
BMC Genomics. 2007;8:27.
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Yu A, Rual JF, Tamai K, He X, Vidal M, Kirchhausen T.
Wnt signaling modulated by Frizzled internalization requires the direct interaction of Dishevelled with the µ2-adaptin of endocytic clathrin adaptors.
Dev Cell 2007;12:129-141.
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Li J, Tewari M, Vidal M, Lee SS.
The 14-3-3 protein FTT-2 regulates DAF-16 in Caenorhabditis elegans.
Dev Biol 2007;301:82-91 .
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