Dana-Farber Cancer Institute (DFCI)  | Dept of Cancer Biology (DFCI)  | Harvard Medical School (HMS)  | Dept of Genetics (HMS)     

2015 Publications 

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  Hawrylycz M, Miller JA, Menon V, Feng D, Dolbeare T, Guillozet-Bongaarts AL, Jegga AG, Aronow BJ, Lee CK, Bernard A, Glasser MF, Dierker DL, Menche J, Szafer A, Collman F, Grange P, Berman KA, Mihalas S, Yao Z, Stewart L, Barabási AL, Schulkin J, Phillips J, Ng L, Dang C, Haynor DR, Jones A, Van Essen DC, Koch C, Lein E.
Canonical genetic signatures of the adult human brain.
Nat Neurosci.2015 Dec;18(12):1832-44.
 
  Grant IM, Balcha D, Hao T, Shen Y, Trivedi P, Patrushev I, Fortriede JD, Karpinka JB, Liu L, Zorn AM, Stukenberg PT, Hill DE, Gilchrist MJ.
The Xenopus ORFeome: A resource that enables functional genomics.
Dev Biol.2015 December 15;408(2):345-57.
 
  Dequeant ML, Fagegaltier D, Hu Y, Spirohn K, Simcox A, Hannon GJ, Perrimon N.
Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization.
Proc Natl Acad Sci U S A 2015 October 20;112(42):12974-9.
 
  Chen AA, Gheit T, Franceschi S, Tommasino M, Clifford GM, Group IHVS
Human Papillomavirus 18 Genetic Variation and Cervical Cancer Risk Worldwide.
J Virol 2015 October; 89:10680-10687.
 
  Sharma A, Menche J, Huang C, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL.
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes.
Hum Mol Genet 2015 Jun 1;24(11):3005-20.
 
  Baruch Barzel, Yang-Yu Liu, Albert-László Barabási.
Constructing minimal models for complex system dynamics.
Nat Commun.2015 May 20;6:7186.
  Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S, Hill DE, Vidal M, Walhout AJ.
Human gene-centered transcription factor networks for enhancers and disease variants.
Cell. 2015 Apr 23;161(3):661-73.
 
  Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJ, Lindquist S, Vidal M.
Widespread macromolecular interaction perturbations in human genetic disorders.
Cell. 2015 Apr 23;161(3):647-60.
 
  Ohashi M, Holthaus AM, Calderwood MA, Lai C-Y, Krastins B, Sarracino D, Johannsen E.
The EBNA3 Family of Epstein-Barr Virus Nuclear Proteins Associates with the USP46/USP12 Deubiquitination Complexes to Regulate Lymphoblastoid Cell Line Growth.
PLoS Pathog.2015 April 9;11(4):e1004822.
 
  Chiassian SD, Menche J, Barabási AL.
A DIseAse MOdule Detection (DIAMOnD)Algorithm Derived from a Systematic Analysis of Connectivity Patterns of Disease Proteins in the Human Interactome.
PLoS Comput Biol.2015 April 8;11(4):e1004120.doi.
 
  Yang F, Petsalaki E, Rolland T, Hill DE, Vidal M, Roth FP.
Protein domain-level landscape of cancer-type-specific somatic mutations.
PLoS Comput Biol. 2015 Mar 20;11(3):e1004147.
 
  Menche J, Sharma A, Kitsak M, Ghiassian SD, Vidal M, Loscalzo J, Barabási AL.
Uncovering disease-disease relationships through the incomplete human interactome
Science. 2015 Feb 20;347(6224):1257601.
 
  Lin GN, Corominas R, Lemmens I, Yang X, Tavernier J, Hill DE, Vidal M, Sebat J, Iakoucheva LM.
Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases.
Neuron. 2015 Feb 18;85(4):742-54.
 
  Taşan M, Musso G, Hao T, Vidal M, MacRae CA, Roth FP.
Selecting causal genes from genome-wide association studies via functionally coherent subnetworks.
Nat Methods 2015 Feb;12(2):154-9.
 
 

 

 

 

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